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Allergic reaction, including swelling at the injection site, rash, or hives · hip, knee, or other joint pain · headache · progression of. Individuals also tend to notice their fingers feeling swollen or their faces feeling fuller at doses of four iu and above. This side effect is temporary and has. Adult growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement. Frontiers in endocrinology, 4. This treatment helps restore natural hgh in your body without the negative effects of hgh injections. 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